This work stems from my M.Sc. Thesis Project, which led us to study L1TD1
, an embryonic stem cell marker, in the context of colorectal cancer. With the meta-analysis of 900+ clinical samples, we uncovered that L1TD1
is a prognostic marker in colon cancer. We discovered that a higher L1TD1
expression associates with a prolonged disease-free survival (despite adjusting for various clinical parameters like Stage, KRAS
mutation status, etc.). We subsequently filed a patent
based on our findings.